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K009382PAnti-IL10 Polyclonal Antibody
物品单位 价格 品牌
960 solarbio
  • 产地:北京
  • 货号:K009382P
  • 发布日期: 2020-03-04
  • 更新日期: 2020-03-05
产品详细说明
CAS编号
抗体名 Anti-IL10 Polyclonal Antibody
是否单克隆
靶点 IL10
用途范围 WB 1:500-2000. IHC 1:50-100.
形态 液体
宿主 Rabbit
标记物
纯度 %
免疫原 Recombinant protein of human IL10
产地 北京
品牌 solarbio
货号 K009382P
保存条件 Store at -20°C. Avoid freeze / thaw cycles.
应用范围 WB IHC
抗原来源
保质期
规格 50ul
产品用途 蛋白研究,分析,检测
克隆性
适应物种 Human Mouse Rat
亚型 IgG
标识物
浓度 %
是否进口
背景资料:The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
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